GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs4294134 | 1 | rs10234309 | chr7:135311167 | PL-5283 | chr7:135347221-135378160:+ | 0.65 | 9.15 | 3.51E-18 | Paget's disease |
| BLCA | cis | rs2243480 | 1 | rs10247526 | chr7:65780696 | CCT6P1 | chr7:65216092-65228661:+ | -0.37 | -4.92 | 1.28E-6 | Diabetic kidney disease |
| BLCA | cis | rs9815354 | 1 | rs1025646 | chr3:41754422 | ULK4 | chr3:41288091-42003660:- | 0.67 | 10.14 | 1.45E-21 | Diastolic blood pressure |
| BLCA | cis | rs10256972 | 1 | rs10256972 | chr7:1039003 | ZFAND2A | chr7:1192544-1199855:- | 0.35 | 5.83 | 1.2E-8 | Longevity;Endometriosis |
| BLCA | cis | rs2143950 | 1 | rs1028449 | chr14:35512995 | PPP2R3C | chr14:35554679-35591679:- | 0.25 | 3.86 | 0.000131 | Atopic dermatitis |
| BLCA | cis | rs7655841 | 1 | rs1030831 | chr4:130025037 | C4orf33 | chr4:130014829-130033842:+ | -0.33 | -5.35 | 1.49E-7 | Chronic obstructive pulmonary disease (moderate to severe) |
| BLCA | cis | rs7655841 | 1 | rs1037147 | chr4:130025873 | C4orf33 | chr4:130014829-130033842:+ | -0.33 | -5.38 | 1.33E-7 | Chronic obstructive pulmonary disease (moderate to severe) |
| BLCA | cis | rs2243480 | 1 | rs1039664 | chr7:65449716 | CCT6P1 | chr7:65216092-65228661:+ | 0.3 | 4.29 | 2.25E-5 | Diabetic kidney disease |
| BLCA | cis | rs10404486 | 1 | rs10404486 | chr19:53284135 | ZNF600 | chr19:53268750-53290034:- | 0.28 | 4.81 | 2.14E-6 | Phospholipid levels (plasma) |
| BLCA | cis | rs7258015 | 1 | rs10408916 | chr19:10447770 | YIPF2 | chr19:11033446-11039357:- | 0.25 | 3.99 | 7.79E-5 | Systemic lupus erythematosus or rheumatoid arthritis |
| BLCA | cis | rs4803468 | 1 | rs10409485 | chr19:41920765 | B3GNT8 | chr19:41931265-41934635:- | 0.21 | 3.94 | 9.68E-5 | Height |
| BLCA | cis | rs4803468 | 1 | rs10413735 | chr19:41921071 | B3GNT8 | chr19:41931265-41934635:- | -0.22 | -4.09 | 5.33E-5 | Height |
| BLCA | cis | rs4803468 | 1 | rs10417311 | chr19:41902038 | B3GNT8 | chr19:41931265-41934635:- | -0.21 | -4.04 | 6.41E-5 | Height |
| BLCA | cis | rs4803468 | 1 | rs10422783 | chr19:41906436 | B3GNT8 | chr19:41931265-41934635:- | -0.21 | -4.03 | 6.6E-5 | Height |
| BLCA | cis | rs4803468 | 1 | rs10422956 | chr19:41901261 | B3GNT8 | chr19:41931265-41934635:- | -0.21 | -4.03 | 6.6E-5 | Height |